T3 usage

[Ricky189]

Sorry if this has been covered but I did a search and couldn't find anything.

What is the best was to use T3s safely? I have read no more than 6 weeks. Starting with 25mcgs ed going up 25 every 4 days til 100mcgs then tapering back down. Is that accurate? And I should have some clen shortly. Ive read I can that with it for 2 weeks at a time....does that sound right?

And is there anything pill or supplement wise I need to avoid while taking T3 and clen?

[kj1212]

The T3 does need to be tapered up and down. You may want to peak at 75 rather than 100. 6 weeks tops. This is what I took for 5 weeks: 25/50/75/50/25. And youre right on the clen. 2 weeks on, 2 weeks off. Start low to see what you can handle, it affects people differently.

[maxgtl]

I have had a lot of success with using it along with clen the way mentioned above for three weeks at a time. I did a ton of research and read it was best at three weeks with the clen and taking benadrel would not be necessary. I would rotate that for three weeks and then ECA (ephedrine, caffine, aspirin) three weeks and back to the T3 and clen. Take it seriously and remember nothing is going to work to give you the results you want without a proper diet and exercise anyway.

[Action]

Originally Posted by Ricky189

Sorry if this has been covered but I did a search and couldn't find anything.

What is the best was to use T3s safely? I have read no more than 6 weeks. Starting with 25mcgs ed going up 25 every 4 days til 100mcgs then tapering back down. Is that accurate? And I should have some clen shortly. Ive read I can that with it for 2 weeks at a time....does that sound right?

And is there anything pill or supplement wise I need to avoid while taking T3 and clen?

Try doing a search under Cytomel. There may be some good topics under that search string on it.

[Action]

Originally Posted by maxgtl

I have had a lot of success with using it along with clen the way mentioned above for three weeks at a time. I did a ton of research and read it was best at three weeks with the clen and taking benadrel would not be necessary. I would rotate that for three weeks and then ECA (ephedrine, caffine, aspirin) three weeks and back to the T3 and clen. Take it seriously and remember nothing is going to work to give you the results you want without a proper diet and exercise anyway.

The only problem with that is that using Clen in conjunction with ECA does not give your beta receptors any downtime to get back to normal. Clen affects your beta-2 receptors and downregulates them. It becomes ineffective around the 14 day mark which is why we cycle it on and off or use Benadry or Ketotifen which is much more effective. Unfortunately, using Ephedrine during Clen off times is a no no, because it also affects the beta receptors so you're not giving them any downtime and when you go back on Clen you're not going to make any progress.

[maxgtl]

Thanks, Action. As always you are correct. I was going to take your word for it anyway, but wanted to find out where I was reading you could do that. I couldn't find the exact location, but found other sites saying it was a myth that was completely incorrect because of exactly what you said- hitting the same beta 2 receptors. I have been on it for about 3 weeks now, 3 weeks of ECA before that, and 3 weeks of the t3 and clen before that, and lastly 3 weeks on another cycle of ECA before that, making it a total of 12 weeks. I am going to finish cycling off this for the next two to three days and start taking 50 to 100 mgs of benedryl tonight for a week as I read I should. Correct me if this is incorrect.
Thanks for looking out for me.

[Action]

Originally Posted by maxgtl

Thanks, Action. As always you are correct. I was going to take your word for it anyway, but wanted to find out where I was reading you could do that. I couldn't find the exact location, but found other sites saying it was a myth that was completely incorrect because of exactly what you said- hitting the same beta 2 receptors. I have been on it for about 3 weeks now, 3 weeks of ECA before that, and 3 weeks of the t3 and clen before that, and lastly 3 weeks on another cycle of ECA before that, making it a total of 12 weeks. I am going to finish cycling off this for the next two to three days and start taking 50 to 100 mgs of benedryl tonight for a week as I read I should. Correct me if this is incorrect.
Thanks for looking out for me.

No worries my friend. That's what we're all here for, to listen and learn.

Yes, it's been awhile since I read up on Clen + Ephedrine hitting the Beta receptors but I remember it going something like this: Clen hits the Beta 1 + 2 receptors and Ephedra hits the Beta 1, 2 and 3 receptors. Something to that effect.

[espiros]

Originally Posted by Action

No worries my friend. That's what we're all here for, to listen and learn.

Yes, it's been awhile since I read up on Clen + Ephedrine hitting the Beta receptors but I remember it going something like this: Clen hits the Beta 1 + 2 receptors and Ephedra hits the Beta 1, 2 and 3 receptors. Something to that effect.

Correct in all counts as usual Action....Now, as a sugestion...I had tried them both and in my opinion the ECA stack is by far superior than the clen /T3 combo with the great advantage that the ECA combo can be used for a longer period not as with Clen where you need to go ON/OFF every 2 weeks.

[Sinjin]

Clen is a selective beta 2 agonist. As with all "selective drugs" there is a minor cross activation of the other beta receptors. However if memory serves me correctly, clen is 7 to 1 beta 2 to beta 1 and I'm not sure about beta 3 which is most found in the gut and intestinal smooth muscle and bladder smooth muscle and in adipose tissue (brown more than yellow and beta found more in yellow than brown). Clen was developed for an oral treatment to control bronchial constriction in asthmatics, hence the selective action on the beta 2 agonist (bronchial smooth muscle relaxation). Beta 3 is notorious for extrapyramidal activity (tremors) so it has some function in the CNS but it isn't fully understood. Very few selective Beta 3 drugs are available, which normally means its function is poor. One comes to mind Solabegron which is supposed to be helpful with irritable bowel and overactive bladder. Amibegron is being developed as an attempt to help with anxiety and depression but I've heard the trials haven't gone so well.

[Sinjin]

Chemically, ephedrine found in herbs such as Ma Huang (Ephedra sinica) is a phenylethylamine compound structurally similar to amphetamine, belonging to the class of sympathomimetic protoalkaloids. Sympathomimetic compounds mimic the action of adrenaline (epinephrine)-like neuro-transmitters at peripheral sympathetic neurons and also exert central nervous system effects.

Adrenaline systems control important body functions like blood pressure regulation and wakefulness.

Ephedrine has a1 a2 b1 b2 adrenergic receptor-agonist properties. 40% of the thermogenic activity of ephedrine is reported to be due to the activation of the b3 adrenoreceptors in the adipose tissues. Ephedrine also stimulates thyroid functions and is why it is contraindicated in hyperthyroid patients. As it does increase thyroid function, it will increase metabolic rate but it is short lived.

Ephedrine is referred to as a mixed-acting drug because it activates adrenergic receptors by direct and indirect mechanisms. Direct activation results from binding of the drug to alpha and beta-receptors. Indirect activation results from release of noradrenaline from adrenergic neurons.

[Action]

Originally Posted by espiros

Correct in all counts as usual Action....Now, as a sugestion...I had tried them both and in my opinion the ECA stack is by far superior than the clen /T3 combo with the great advantage that the ECA combo can be used for a longer period not as with Clen where you need to go ON/OFF every 2 weeks.

Yes Espiros. You are correct on that one...Although the only thing I would have to say different from that one, is that in my experience, Clen is the more intense and effective of the two. It also unfortunately comes with a host of side effects that the ECA stack doesn't give me. One of the big reasons for that is the Aspirin effect of the ECA stack. 7

[Ricky189]

Thanks guys. That is awesome info!

[espiros]

Originally Posted by Action

Yes Espiros. You are correct on that one...Although the only thing I would have to say different from that one, is that in my experience, Clen is the more intense and effective of the two. It also unfortunately comes with a host of side effects that the ECA stack doesn't give me. One of the big reasons for that is the Aspirin effect of the ECA stack. 7

Yes....that's another good reason to go with this stack before going with clen and, nothing compares with the "hype" ephedrine with caffeine gives me...I could run a marathon without any problem!!
While with Clen...I suffer doing cardio..because my cardiac rhythm goes higher than usual.

[jamie1984]

why do you take aspirin with epherdrine and caffeine? Also do you get all the caffeine by drinking redbull and coffee all day or can you get caffeine tabs or something. Last Q. is does t3 work effectively on its own without clen as i hate clen it gives me a real bad twitch in y eyes i walk around like a crazy man.

[Action]

Originally Posted by jamie1984

why do you take aspirin with epherdrine and caffeine? Also do you get all the caffeine by drinking redbull and coffee all day or can you get caffeine tabs or something. Last Q. is does t3 work effectively on its own without clen as i hate clen it gives me a real bad twitch in y eyes i walk around like a crazy man.

Think of aspirin as the drug that brings you back to earth after caffeine and ephedrine make you skyrocket! The combination of the 3 is known to give the best and most effective thermogenic combination as opposed to just taking eph or caff on it's own. I personally like the aspirin component because I feel it has a calming effect on my heart rate.

Yes, T3 will work quite effectively on it's own without Clen. But of course, the combination of the 2 is one of the best fat burning stacks out there.

[jamie1984]

Originally Posted by Action

Think of aspirin as the drug that brings you back to earth after caffeine and ephedrine make you skyrocket! The combination of the 3 is known to give the best and most effective thermogenic combination as opposed to just taking eph or caff on it's own. I personally like the aspirin component because I feel it has a calming effect on my heart rate.

Yes, T3 will work quite effectively on it's own without Clen. But of course, the combination of the 2 is one of the best fat burning stacks out there.

thanks action, so the aspirin levels you out, does it make the hyper feeling go aswell? would it do the sae with the feeling you get from len as that is the only reason i dont take it?

thanks action you the man

[Action]

Originally Posted by jamie1984

thanks action, so the aspirin levels you out, does it make the hyper feeling go aswell? would it do the sae with the feeling you get from len as that is the only reason i dont take it?

thanks action you the man

Ya, and combines with the other two for max thermo effect. I do take aspirin with my Clen sometimes when I feel my heart rate going too high and do like the effects.

[Ricky189]

I just got my clen today. It is 50 mcg per capsule. Never used it before. Is one a day all I need? Should I work up to more? Is this going to be too strong for my first time ever trying it?

I was going to take one tomorrow when I first wake up. Im at 100mcg a day with the t3s. 50 in the morning then 25 twice spaced out as evenly as I can throughout the day. And does it matter if I take it on an empty stomache? Ive been trying too then eat half an hour later. And thanks guys. Lots of great info in this post.

[Ricky189]

I did a search and this is what I was thinking. Ive got 50 clen caps of 50 mcgs. 2 weeks on 2weeks off with benadryl in between. Each of the 2 week periods I will use one cap for 5 days and 2 caps for 9 days then stop. That will use all 50 caps up. Is this the most efficient way to take them and safely?

I'd still like to know if I should take the clen and t3s on an empty stomach.

After this is done I think I will try ECA again as the first time I used it....like 10 years ago(f@ck I'm getting old...lol)....I dropped 15 or 20lbs of weight, all fat in 2 weeks. It was amazing but the effects slowed down quickly after that and it never worked the same again. I used it on and off over the years and all it ever did was give me energy. But I never tried taking benadryl with it so I'll give it another shot. Much easier as you can buy ephedrine here OTC for like $6. Do the beta receptors clear up on thier own over time or do they stay saturated until you use the benadryl?

[espiros]

Originally Posted by Ricky189

I did a search and this is what I was thinking. Ive got 50 clen caps of 50 mcgs. 2 weeks on 2weeks off with benadryl in between. Each of the 2 week periods I will use one cap for 5 days and 2 caps for 9 days then stop. That will use all 50 caps up. Is this the most efficient way to take them and safely?

I'd still like to know if I should take the clen and t3s on an empty stomach.

After this is done I think I will try ECA again as the first time I used it....like 10 years ago(f@ck I'm getting old...lol)....I dropped 15 or 20lbs of weight, all fat in 2 weeks. It was amazing but the effects slowed down quickly after that and it never worked the same again. I used it on and off over the years and all it ever did was give me energy. But I never tried taking benadryl with it so I'll give it another shot. Much easier as you can buy ephedrine here OTC for like $6. Do the beta receptors clear up on thier own over time or do they stay saturated until you use the benadryl?

Clen, you will be fine to start with 50 mcgs, then you will need to ramp up and down as you do with T-3.

Benadryl, is good because as you said, clears you receptors so, this way you can be on clean for longer than 2 weeks, which is about the time it takes your receptors to get desensitized by it, otherwise use clen 2 weeks on and 2 off as you planning, in other words if you are going to do it this way then, benadryl will not be need it.

[Ricky189]

Thanks.

I took 50 mcgs today first thing in the morning on an empty stomache and didn't feel much of an effect from it other than a little bit warm for a while. How high should I go for a daily dose? Would I maybe be better off using it for 4 weeks in a row and work upt to 150 or 200mcgs a day and taper back down instead of only getting up to 100mcgs a day in 2 seperate 2 week periods?

[espiros]

You will know how high to go by the feeling CLEN gives you, most people go to 100, 120....I can go all up to 200 but, at that high of a dose the sides could get bad...tremors, palpitations, dizziness, so, keep it safe...go 100 to 120.
Now, I rather go 2 on with 2 off but, again you will learn what way works better for you from personal experience.

[Ricky189]

When I take 2 caps which is 100mcgs...should i try to take them several hours apart or both in the morning?

[espiros]

Originally Posted by Ricky189

When I take 2 caps which is 100mcgs...should i try to take them several hours apart or both in the morning?

I take all at once so you get the full effect, The effect on Clen last only few hours, in me about 2 and at the most 3 same like with ephedrine.
So, I take it all at once about 30 mins before work out.