diretics

[badstone]

Pharmaceutical Name: Spironolactone
Chemical structure: 17-hydroxy-7alpha-mercapto-3-oxo-17alpha- pregn-4-ene-21-carboxylic acid gamma-lactone acetate
Molecular weight of base: 416.5744

Spironolactone is a steroid, although it is commonly used as a diuretic. The basis for this is simple - it inhibits aldosterone production and as a result as a diminishing effect on water retention, allowing bodybuilders to achieve that "ripped" look. Aldosterone regulates the overall level of water stored by the body and does so by increasing electrolyte counts. Sprionolactone can signal your body to release water due to its manipulation of aldosterone. The natural use of this steroid is to reduce water rentention and as a result, increase overall condition. This makes spironolactone an attractive choice for competitive bodybuilders and models.

In the medical community, spironolactone is used as a diuretic when toxins have been consumed, and also as an anti-hypertensive drug. Spironolactone has no effect on potassium levels so electrolyte balance is not a concern with its use. This makes it a much safer alternative than lasix for use as a diuretic.

Sprionolactone may have some value in reducing androgenic side effects, because it blocks the androgen receptor. As a result of this, for every side effect you block, there will be a resulting loss in overall gain. Therefore it should not be used for this express purpose since the ultimate way to eliminate all side effects from concurrent use with another steroid would be to eliminate all gains - in which case using steroids to begin with would not be necessary.

Spironolactone can be used post cycle and be effective. A bodybuilder's goal post cycle is to speed up the process of normalization as much as possible. This includes recovery of the HPTA and increasing levels of natural testosterone production to a normal level. The way in which testosterone is brought back up post cycle is through eliminating negative feedback. Sprironolactone can be run at the end of treatment with nolvadex and clomid and alongside HCG. This will have an effect on reducing the quantity of side effects from the HCG such as water retention and acne, and will also provide a synergistic effect with the clomid or nolvadex treatment to reduce water retention and halt additional side effects. Side effects from a steroid cycle are normally seen during the course of the cycle itself, but may also arise after the cycle has been discontinued. The used of spironolactone can prevent such side effects for occurring to begin with or greatly diminish their impact.

Spironolactone is not perfect for reducing androgenic side effects, but nothing really is, as side effects are some of the risks bodybuilders choose to take to gain more muscle mass and strength. Sprironolactone is very good at controlling side effects post cycle, at a point where gains cannot be inhibited since steroid use has been ceased. It should be noted that aldosterone inhibitors and other diuretics have side effects of their own. Cramping is one such effect. Sodium and potassium are the two electrolytes most effect by the use of diuretics, and they are essential to the contraction of muscles. So cramping can occur when these two electrolytes are manipulated. Diarrhea, anxiety, dehydration and weakness are also associated with diuretic use.

SIDE EFFECTS


As mentioned above, possible side effects from the use of aldactone (or any other diuretic) include cramping, diarrhea, dehydration and weakness.

STACKING AND USE


To prepare for a bodybuilding competition or a photo shoot (if a model is using aldactone), an individual would use 75-100 mg of aldactone per day for the 5-10 days nearest to the competition. One dose, taken first thing in the morning, would be one method in which aldactone could be used. Aldactone is a relatively mild diuretic (compared to, for example, lasix), and the higher the dose, the greater the effect. As a result of the higher dose, the possibility of anti-androgenic effects such as muscle a greater amount of muscle loss, are possible. If a user is planning on running aldactone post cycle as part of post cycle therapy 50-100 mg per day starting 1-1.5 weeks after your last shot of a long lasting androgen and this should be ran until the end of post cycle therapy (usually 4-5 weeks later).

Aldactone acts as an anti-androgen, counters bloating and water retention and is used as an anti-hypertensive.

The use of ancillaries is relatively useless here, because it acts as an anti-androgen, counters bloating and water retention and is used as an anti-hypertensive. So the common steroid side-effects are of no concern with the use of spironolactone.

[dieseld]

Another informative post Bad! How much personal experience do u have with it? How is it for pct? Is there much loss of muscle or strength post pct?

[badstone]

I only use it precontest. Its safer than lasix. For PCT letro is a great choice and it will get the water off also. You can also sodium load to get water off..... Vitamin B6 at high doses also drops water. I have only used it once but it seems to work great.....

[dieseld]

Thanks Bad, for others benefit at what dose and how many days out works best for you?

[badstone]

About one week out 100mg a day....
I dont know about using it for PCT. Some one could try it and see how it works.

[crazedhate]

ever try or hear feedback on MHP Xpel? or are "natural" diuretics junk??
thanks

[badstone]

Originally Posted by crazedhate

ever try or hear feedback on MHP Xpel? or are "natural" diuretics junk??
thanks

Yes I have heard it works good. I have never tried it though.....

[chiselmeat]

Would you expect Spironolactone to be available from one of our sources?

[badstone]

Originally Posted by chiselmeat

Would you expect Spironolactone to be available from one of our sources?

I dont think so. I will look for a source.

[chiselmeat]

Originally Posted by badstone

I dont think so. I will look for a source.

Thanks I am interested..............