![]() |
|
|
|||||||
| Archived Greats Discuss Why we Should all use Exemestane in the Steroid forums; Okay members, here is a piece of information i would like all of to know, this info is of importance ... |
|
|
LinkBack | Thread Tools | Display Modes |
|
#1
|
|||
|
|||
|
Okay members, here is a piece of information i would like all of to know, this info is of importance as I for one still love my aridmidex and also my exemestane, i never do a cycle without exemestane, so if you are looking to control estrogen and keep it at bay, than i would suggest you experiment with what works for you, some will like adex and some say it makes them feel like shit, on the other hand exemestane is know to make one feel awake and great while on as opposed to adex. UR
Aromasin (exemestane) is a steroid-al AI - an irreversible aromatase inhibitor ... great for controlling estrogen "during cycle" and "PCT" ... But, what else does it do ??? Good reading.... ABSTRACT FROM JOURNAL OF CLINICAL ENDOCRONOLOGY AND METABOLISM Suppression of estrogen, via estrogen receptor or aromatase blockade, is being investigated in the treatment of different conditions. Exemestane (Aromasin) is a potent and selective irreversible aromatase inhibitor. To characterize its suppression of estrogen and its pharmacokinetic (PK) properties in males, healthy eugonadal subjects were recruited. In a cross-over study, 12 were randomly assigned to 25 and 50 mg exemestane daily, orally, for 10 d with a 14-d washout period. Blood was withdrawn before and 24 h after the last dose of each treatment period. A PK study was performed (n = 10) using a 25-mg dose. RESULTS : The 25- and 50-mg doses of daily exemestane had comparable effects in suppressing circulating estrogen concentrations, with 38 ± 24% (mean ± SD; P = 0.002 vs. baseline) and 32 ± 29% (P = 0.008) decreases in estradiol concentrations, 71 ± 12% (P < 0.0001) and 74 ± 12% (P < 0.0001) decreases in estrone concentrations, and 45 ± 27% (P = 0.004) and 51 ± 20% (P = 0.02) BUT THERE'S MORE There was an increase in circulating testosterone concentrations after both 25 mg (60 ± 58%; P = 0.001) and 50 mg (56 ± 48%; P = 0.003) exemestane. Androstenedione concentrations were increased as well after 25 mg (32 ± 36%; P = 0.004) and 50 mg (47 ± 59%; P = 0.052) exemestane, respectively (Fig. 1Go and Table 2Go). SHBG concentrations were decreased by 21 ± 7% (P = 0.0003) and 19 ± 39% (P = 0.18) at 25 and 50 mg exemestane, respectively. Free testosterone concentrations were increased by 117 ± 74% (P = 0.0001) and 154 ± 95% (P < 0.0001) at both doses, due to the decrease in SHBG and the increase in total testosterone. THE ICING ON THE CAKE ! There were no changes in circulating serum triglycerides, cholesterol, or LDL or HDL cholesterol concentrations with either dose of exemestane. |
|
#2
|
|||
|
|||
|
What dosage would you recommend for someone trying to prevent gyno during a cycle if they're gyno prone?
|
|
#3
|
|||
|
|||
|
between 25-50mg ed. this would prevent it completely.
|
|
#4
|
|||
|
|||
|
Thanks bro. I started to get some symptoms with my last cycle towards the end, so I wanna be on top of that shit in the future. I've got a buddy trying to fight some gyno and I don't wanna go down that route, but then again I also know not to use pro-hormones as a way of doing pct
|
|
#5
|
|||
|
|||
|
Good read
__________________
Please do not message me with steroid related questions. Posting in the forums will get you a quicker answer, and help other people in a similar situation, it helps the board grow. Thank you. |
|
#6
|
||||
|
||||
|
so let me c if i got this right, aromasin will not only prevent gyno but can also help your test levels....very cool thanks UR
|
|
#7
|
||||
|
||||
|
nice read, but to bad Aromasin is so hard to find.
|
|
#8
|
||||
|
||||
|
and very expensive per mg also.......
|
|
#9
|
|||
|
|||
|
Quote:
Correct, their was a huge debate and discussion about 4-6 months back, where If Im correct a few members were dealing with gyno issues, theseare a few of the compounds I stated than, but so many opinions and it just confused many members, well the info is here now. very true, But I can get it, make it myself, and its very cheap, but like you said, not everybody carry it as it is a expensive compound. how about 50grams for $400, thats what i get it for, and canadians love it. lol |
|
#10
|
||||
|
||||
|
Quote:
|
|
#11
|
||||
|
||||
|
Quote:
|
| Thread Tools | |
| Display Modes | |
|
|